![]() ![]() The results show that the drug caused a slight lowering of adrenal corticosteroid secretion. In a study evaluating the effects of mometasone furoate cream on the HPA axis, 15 grams were applied twice daily for 7 days to six adult subjects with psoriasis or atopic dermatitis. This may be done by using the adrenocorticotropic hormone (ACTH) stimulation test. Because of the potential for systemic absorption, use of topical corticosteroids may require that patients be periodically evaluated for HPA axis suppression. Factors that predispose a patient using a topical corticosteroid to HPA axis suppression include the use of high-potency steroids, large treatment surface areas, prolonged use, use of occlusive dressings, altered skin barrier, liver failure and young age. Manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on treatment. This may occur during treatment or after withdrawal of treatment. Warnings and Precautions Effects on Endocrine System Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency. Contraindications Mometasone furoate cream, 0.1% is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation. Each gram of Mometasone Furoate Cream USP, 0.1% contains 1 mg of mometasone furoate, USP in a white to off-white, uniform and smooth cream. It is not for oral, ophthalmic, or intravaginal use. Mometasone furoate cream, 0.1% is for topical use only. Avoid use on the face, groin, or axillae. Do not apply mometasone furoate cream, 0.1% in the diaper area if the patient still requires diapers or plastic pants, as these garments may constitute occlusive dressing. Do not use mometasone furoate cream, 0.1% with occlusive dressings unless directed by a physician. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Therapy should be discontinued when control is achieved. Since safety and efficacy of mometasone furoate cream, 0.1% have not been established in pediatric patients below 2 years of age use in this age group is not recommended. Mometasone furoate cream, 0.1% may be used in pediatric patients 2 years of age or older. do not use it on the face, groin, or underarms, or for diaper rash, unless directed to do so by your doctor.Related/similar drugs prednisone, methotrexate, Humira, Dupixent, Remicade, cyclosporine, Stelara Mometasone Cream Dosage and Administration Apply a thin film of mometasone furoate cream, 0.1% to the affected skin areas once daily.This medication is for use only on certain areas of skin: Tell your doctor if your condition does not improve after 2 weeks of treatment or if it worsens.Are trying to get pregnant, are already pregnant or you’re breastfeeding.Have broken skin, cuts or itchy skin which is not inflamed or red.Have ever had an allergic reaction to mometasone or any other medicine in the past.Tell a doctor or pharmacist before using it if you: Wait at least 10 minutes before using any other creams or ointments.Wash your hands afterwards (unless you are treating the skin on your hands). ![]() Be careful not to get the cream or ointment on broken skin or cuts.Use the cream or ointment on all the irritated skin, not just the worst areas.Carefully smooth it into your skin in the direction that your hair grows.Spread the cream or ointment in a thin layer over the area of irritated skin.Wash and dry your hands and then squeeze out the right amount.Do not cover the treated area with bandages or other dressings unless instructed to do so by your doctor.Apply as directed by your doctor, usually a thin film of medication to the affected area once daily.Used to avoid flare-ups and reduce eczema-induced red, itchy and dry skin.It is known as a "powerful corticosteroid." These medicines are placed on the surface of the skin to reduce the redness and itchiness caused by some skin problems.Mometasone is one of the topical corticosteroids medicines.It works by activating natural substances in the skin to reduce swelling, redness, and itching.Mometasone topical is used to relieve the redness, swelling, itching and inflammation and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). ![]()
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